Pseudohypoparathyroidism (PHP) encompasses a group of rare and heterogeneous metabolic disorders that share a common feature, namely impairment in various hormone signaling pathways that activate cyclic adenosine monophosphate (cAMP) via the Gsα protein and promote resistance to parathyroid hormone (PTH) [1]. This evidence concerns the gene GNAS and pseudohypoparathyroidism type 1A.