Serum prolactin (PRL) levels were significantly lower in the treated group than in the untreated group (median PRL: 17.6 vs. 43.1 ng/ml, P = 0.003), and we found no significant differences in the ratio of microadenomas to macroadenomas or the maximum diameter of adenoma between the treated and untreated groups (P > 0.05). The gene discussed is PRL; the disease is adenoma.