IL17F and colorectal cancer: However, for the IL-17F rs763780 polymorphism, a decreased risk correlated with colorectal cancer in the Caucasian subgroup was observed in the recessive and homozygous models, which suggested that the biological functions of the IL-17F rs763780 polymorphism for populations from various races were possibly discrepant and provided a negative predictor for colorectal cancer occurrence in Caucasians; however, due to the insufficient sample size, such a result needs to be identified by further studies.