As shown in Table 2, in the 225 CRC samples, positive B7-H4 expression was correlated with moderate/poor differentiation (χ2 = 8.992, P = 0.003), lymph node metastasis (χ2 = 8.919, P = 0.003) and advanced Dukes’ stage (χ2 = 5.427, P = 0.02) and that positivity for p-PKCδ was correlated with advanced Dukes’ stage (χ2 = 4.118, P = 0.042). The gene discussed is PRKCD; the disease is colorectal carcinoma.