More recently, 7,12-dimethylbenz[a]anthracene (DMBA) and 12-O-tetradecanoylphorbol-13-acetate (TPA) were reported to induce the development of cSCC in the mouse by the enhancement of the IL-23/IL-17 signaling pathway [97]. The gene discussed is IL17A; the disease is skin squamous cell carcinoma.