E2F7 and hepatocellular carcinoma: In these studies, it was found that the expression of miR-424-5p in tissues and cells of patients with HCC was decreased, and as verified by dual-luciferase reporter gene assays, the proliferation, invasion and migration of HCC cells were inhibited by targeting the inhibition of the expression of YAPI [45], TRIM29 [46], E2F7 [47] or ICAT [48].