CASP3 and acute myeloid leukemia: On the other hand, our results showed that the RNA expression levels of intrinsic and extrinsic signals of apoptosis, such as Fas, casp3 and bax, in the testicular tissue of immature mice treated with AML or CYT (alone) or in combination (AML+CYT) were similar to those of the control group (Figure 3C).