Numerous activated CD4+ T lymphocytes were found in the bronchial mucosa of asthmatic patients, while various cytokine levels by CD4+ T lymphocytes, including Th1, Th2, Th9, and Th17 cells, augmented antigenic challenges, subsequently accompanied with local eosinophilia and bronchial hyperresponsiveness (BHR) [2]. The gene discussed is CD4; the disease is Increased total eosinophil count.