CCL5 and inflammatory response: Ccr3; that is, C-C motif chemokine receptor type 3 (CD193), highly expressed in eosinophils, basophils, Th1 cells, Th2 cells, and airway epithelial cells for ligand eotaxins, RANTES, monocyte chemotactic protein (MCP)-2, MCP-3, and MCP-4, plays a vital role in promoting allergen-induced airway inflammation and hyperresponsiveness by mostly regulating eosinophils and mast cells [24,25,26]; however, Ccr3 has weak specificity in regard to activating basophils to release histamine [27].