CCL2 and immune system disorder: Human IL-8 (C–X–C motif chemokine ligand 8, CXCL-8), monocyte chemoattractant protein-1 (MCP-1; C–C motif chemokine ligand 2, CCL2), and regulated upon activation, normal T-cell expressed and secreted (RANTES; C–C motif chemokine ligand 5, CCL5) are central proinflammatory chemokines which serve as important mediators of inflammation and immunological processes in several inflammatory and immune diseases.