More specifically, PTPs such as PTPN1, PTPN2, PTPN9, PTPN11, PTPRF, and DUSP9 are associated with the pathogenesis of type 2 diabetes, as they negatively modulate insulin signaling and induce insulin resistance [6,7,8,9,10,11,12]. Here, PTPN9 is linked to Insulin resistance.