Hence, seminal exosomes (including prostasomes and epididymosomes) isolated from samples of normozoospermic individuals were shown to contain higher levels of aquaporin 5 (AQP5), solute carrier family 13 member 2 (SLC13A2), transient receptor potential cation channel subfamily V member 6 (TRPV6), and zinc transporter 4 (SLC30A4) than seminal exosomes collected from patients with severe or moderate asthenozoospermia [128,129]. Here, AQP5 is linked to Reduced sperm motility.