In the present study, it was observed that in the endometria from women with obesity and IR (with or without PCOS), lower levels of p-AS160 and GLUT4 were detected and that these levels increased after MTF treatment, which agrees with the study of Carvajal et al., 2013 [17]. Here, SLC2A4 is linked to obesity due to melanocortin 4 receptor deficiency.