There are recent reports of its deregulation in different cancer types; for example, Myo1a seems to be a tumor suppressor in the intestine [30], Myo1e promotes tumor proliferation and cell de-differentiation in breast cancer [31], and Myo1b overexpression promotes increased cell migration and lymph node metastasis in head and neck cancer [32]. The gene discussed is MYO1E; the disease is cancer.