In addition, dual inhibition of H3K9me2 and H3K27me3 with the G9a inhibitor, UNC0638 (1 μM), and the EZH2 inhibitor, GSK126 (1 μM), suppresses multiple myeloma cell proliferation by inducing cell cycle arrest and apoptosis [28]. This evidence concerns the gene EZH2 and plasma cell myeloma.