In fact, most of the studies associated lactadherin overexpression in tumor samples with the promotion of pro-tumorigenic and pro-metastatic capacities, such as increased tumor cell proliferation, angiogenesis, migration, invasion, and epithelial-to-mesenchymal transition (EMT) [11,19,21,22,39,40,41,42,48]; processes that are related to the physiological function of this protein. This evidence concerns the gene MFGE8 and neoplasm.