NGFR and neuroblastoma: As shown in Figure 1A, in all neuroblastoma cell lines that were examined prolonged exposure (24 h) to either VPA (1 mM) or entinostat (1 μM) increased p75NTR protein levels by several fold (SH-SY5Y: 14.0- and 18.0-fold; LAN-1: 3.9- and 10.0-fold; Kelly: 15.0- and 34.0-fold; IMR-32: 14.8- and 25.0-fold; BE(2)C: 16.7- and 36.0-fold, NB-1: 9.0- and 45.0-fold by VPA and entinostat, respectively; p < 0.001, n = 4).