FTO upregulation in lung cancer cells and the resulting reduced m6A levels on MZF1 and USP7 increased their stability; thereby, promoting oncogenic functions [97,98].In colon cancer cell lines, Tsuruta et al. reported the upregulation of FTO and its target: Programmed death 1 ligand (PD-L1) [99]. The gene discussed is FTO; the disease is malignant colon neoplasm.