TP53 and ovarian carcinoma: To investigate the process of mitotic catastrophe mutant p53 ovarian carcinoma (Caov4), non-small cell lung carcinoma (U1810) cell lines and wild-type p53 colorectal carcinoma (HCT116) cell line were treated with 600 nM of a DNA-damaging drug, doxorubicin, for 48 h according to previously published data [11,20].