Severity of COVID-19 [19] is correlated to the unique inflammatory profile of patients with high serum levels of multiple cytokines and chemokines/growth factors [20]: TNF-α, IL-1, 6 and 12, IFN-gamma, and TGF-beta, CCL2, CXCL9 and 10, and IL-8. The gene discussed is TNF; the disease is COVID-19.