The KEGG signaling pathway enrichment analysis for PCa for EP and PB influenced 81 overlapping genes and also showed that there are 25 genes (GSK3B, CDKN1A, CDKN1B, KLK3, FASLG, HSP90B1, CASP9, MAPK8, CCND1, CDH1, MYC, CASP3, MAPK3, NOS2, EGF, STAT3, IGF1, VEGFA, AR, BCL2, RARA, BAX, BIRC5, MET, TP53) that were markedly enriched with pathways in cancer (Table S8). Here, IGF1 is linked to posterior cortical atrophy.