While these and other genetic alterations associated with clonal hematopoiesis have been reviewed recently [251], one recent advance of note (building on earlier studies [256,257,258,260]) used peripheral blood samples deposited at the United Kingdom Biobank and Mass General Brigham Biobank by individuals (40–70 years old) without a history of hematological malignancy to analyze, by whole exome sequencing and single nucleotide polymorphisms, 55,383 individuals for CHIP and 420,969 individuals for autosomal mCAs [259]. The gene discussed is STUB1; the disease is hematologic disorder.