Notably in these studies, almost half of infant AML cases (0–1 years old) carry KMT2A rearrangements, with a significant proportion bearing the t(9;11)/KMT2A/MLLT3 (MLL/AF9) fusion gene, the incidence of which declines during childhood and adolescence [121]. The gene discussed is KMT2A; the disease is acute myeloid leukemia.