Thus far, previous studies using the form-deprived myopia (FDM) animal model have demonstrated that transforming growth factor-β (TGF-β), metalloproteinase 2 (MMP2), and tissue inhibitor of metalloproteinase-2 (TIMP-2) in sclera are associated with the development of myopia [8,9]. This evidence concerns the gene MMP2 and myopia.