Rg1 also decreased the serum level of malondialdehyde (MDA) and upregulated the expression of superoxide dismutase (SOD) and peroxisome proliferator-activated receptor-alpha (PPARα); this promoted fatty acid beta oxidation and the metabolism of FFAs and TG, indicating that Rg1 improved NAFLD by regulating lipid peroxidation. Here, PPARA is linked to metabolic dysfunction-associated steatotic liver disease.