CHRNA7 is related to several disorders with cognitive deficits, including schizophrenia [9], P50 auditory gating deficits [34], autism [35], epilepsy [36], bipolar disorder [37], attention deficit hyperactivity disorder (ADHD) [38], Down syndrome [39], Parkinson’s disease (PD) [40], and Alzheimer’s disease (AD) [41,42]. The gene discussed is CHRNA7; the disease is early-onset autosomal dominant Alzheimer disease.