The expression of α7 is reduced in multiple areas of postmortem brain specimens from schizophrenic patients and from patients with major psychiatric disorders [55,102,103,104,105,106], and 21 polymorphisms have been identified in the promoter region, most of which decrease transcription and are strongly associated with schizophrenia and P50 deficits [34,107,108]. Here, NFKB1 is linked to schizophrenia.