Their findings indicate that these bioactive molecules regulate the expression of target proteins through enriched signaling pathways (covering PI3k-Akt and Rap1 signaling pathways), inhibit tumor proliferation and metastasis, regulate metabolism, and promote nerve repair by regulating the expression of targets (MAPK3, HADC3, HADC1, RXRA, STAT3, etc.)via multiple pathways: the Notch signaling pathway, EGFR tyrosine kinase inhibitor resistance, and the PI3K-Akt signaling pathway. The gene discussed is AKT1; the disease is neoplasm.