Studies have been carried out on salivary MMP-8 and crevicular MMP-2, which were known to serve as biomarkers of periodontal disease; however, there is a dearth of literature on how type-II diabetes mellitus (type-II DM) influences the levels of MMP-9 in chronic periodontitis patients [11,12]. The gene discussed is MMP9; the disease is periodontal disorder.