Several studies have reported that DET and IDET induce apoptosis in various types of cancer cells through multiple mechanisms, such as cell cycle arrest induction, the promotion of mitochondrial dysfunction, reactive oxygen species (ROS) induction, Bcl-2 family protein modulation, the inhibition of nuclear factor-kappa B (NF-κB), and the inhibition of signal transducers and activators of transcription 3 (STAT3) activation [28,29,30,31,32,33,34,35,36,37]. This evidence concerns the gene NFKB1 and cancer.