In murine mammary adenocarcinoma TS/A cells, DET (2 mg/mL) induced the upregulation of TNF-R1 protein and the activation of downstream caspase-8 through TNF/TNFR-mediated activation, rather than increasing the expression of Fas and FasL proteins [33]. Here, TNFRSF1A is linked to breast adenocarcinoma.