Collective lines of evidence suggest that DET holds the potential to induce extrinsic apoptosis by upregulating Fas/FasL, TNF/TNF-R1, DR4/5, active caspase-10, -8, -7, -3, and tBid formation in various cancer cells, which needs to be explored further using in vivo cancer models. Here, TNFRSF1A is linked to cancer.