IL6 and neoplasm: Several stimuli, such as microbial pathogens, carcinogens, endotoxins, free radicals, interleukin 1 (IL-1), interleukin 6 (IL-6), lipopolysaccharide (LPS), tumor-necrosis factor (TNF), tumor promoter, and radiation (UV-light, X-rays, γ-rays), trigger the activation of NF-κB [4].