SUZ12 and glioblastoma: The main affected pathways in the boundary of the tumour after AM630 exposure (Table 4) were epigenetic markers related to chromatin remodelling via histones modification (i.e., H3K27me3, PCR2 targets, SUZ12 targets) These genes, that are normally expressed in embryonic cells but not in adult tissues are reactivated in tumours as occurs in glioblastoma.