Induction of CCL20 by PGF-2α/FP signaling in an endometrial adenocarcinoma cell line was found to be dependent on intracellular signaling by Gq protein, epidermal growth factor receptor (EGFR), extracellular signal-regulated kinase (ERK), calcineurin, and nuclear factor of activated T cell (NFAT). This evidence concerns the gene EGFR and endometrium adenocarcinoma.