While the roles of TNF-α as an effector Th1 cytokine, and IP-10 as a chemokine involved in monocytes and Th1 cells trafficking into the inflammatory foci are well-known in TB [26,27,28]; other cytokines like IL-22, GM-CSF, IL-5, and IL-13 are less studied. The gene discussed is TNF; the disease is tuberculosis.