Pattern recognition receptors (PRRs), including Toll-like receptors, RIG-I-like receptors, NOD-like receptors, and C-type lectin receptors, play an important role in host immunity against Aspergillus; thus, the genetic defects in PRRs may lead to susceptibility to aspergillosis [5,6,7]. This evidence concerns the gene CLEC4D and aspergillosis.