As for NLRs, previous studies have shown that rs2066842 in NOD2 of donors was associated with the risk of invasive aspergillosis after hematopoietic stem-cell transplantation, while rs212704 and ACTT (rs212704 rs455060 rs7562653 rs385076) in NLRC4 were associated with A. fumigatus colonization in cystic fibrosis patients [23,24]. Here, NOD2 is linked to cystic fibrosis.