CRP and obesity due to melanocortin 4 receptor deficiency: Concerning the pathogenic role of CRP in autoimmune diseases, it has been reported that SLE patients could have higher CRP serum levels compared to healthy controls [10], and the CRP serum levels correlate with traditional cardiovascular risk factors such as dyslipidemia, obesity, and glucose disturbances, which could be associated with a negative impact on robust outcomes such as damage, disease activity, and survival in SLE [11].