To compare the biochemical and cardiometabolic statuses according to the CVD risk by the criteria from the center for disease control and prevention and the American Heart Association to CRP serum levels, both SLE patients and CS were stratified according to CRP levels as low CVD risk (<1 mg/dL), average CVD risk (≥1 to <3 mg/dL) and high CVD risk (≥3 mg/L). The gene discussed is CRP; the disease is systemic lupus erythematosus.