Regarding cardiometabolic status, in SLE patients we observed a positive correlation between triglycerides levels (r = 0.18; p = 0.01), the Castelli index (r = 0.35; p < 0.001), the Kannel index (r = 0.23; p < 0.01), the triglycerides-HDL-C ratio (r = 0.38; p < 0.001), and CMI score (r = 0.21; p = 0.03), and a negative correlation between LDL-C (r = −0.24; p = 0.001), and HDL-C (r = −0.37; p < 0.001) with CRP levels. The gene discussed is CRP; the disease is systemic lupus erythematosus.