Interestingly, when analyzing the concentration of CCL2 in the control group and the study group by TNM stage, we showed a significant relationship between stage III and the control group, which may be a confirmation of the Watanabe et al. [19] investigation, which pointed out the relationship between CCL2 and the appearance of local lymph node metastases. The gene discussed is CCL2; the disease is metastatic malignant neoplasm in the lymph nodes.