CDC73 and inflammatory response: The Wnt/β-catenin signaling pathway is an attractive candidate mediator of chronic hepatic inflammation, and parafibromin (cell division cycle 73, CDC73) binds stably to β-catenin in the nuclei of hepatocytes to form parafibromin/β-catenin complex, which induces the expressions of Wnt target genes such as cyclnD1 and c-myc [11,12].