Although the association between CRP and the activity of autoimmune disease is well known and highly suggestive for a causal involvement in this heterogeneous group of diseases (like rheumatoid arthritis, ulcerative colitis, Crohn’s disease, psoriasis, giant cell arteritis etc.)[30], there are no studies on specific CRP inhibition in autoimmune disease. This evidence concerns the gene CRP and rheumatoid arthritis.