Surprisingly, Jäger et al. showed that after the cessation of P2Y12 inhibitor therapy in CAD patients, plasma levels of miR-21, miR-126, miR-150 and miR-223 remained unaltered; however, the expression of these miRNAs was affected by the P2Y12 inhibitor choice, being increased in patients taking ticagrelor as compared to clopidogrel and prasugrel [51]. Here, P2RY12 is linked to coronary artery disorder.