Akt (protein kinase B), ERK1/2 (Extracellular signal-regulated kinase 1/2) and p53/AMPK/mTOR (cellular tumor antigen p53/AMP-activated Protein Kinase/mammalian target of rapamycin)-induced autophagy signaling pathways were also reported as targets of resveratrol on RCC, leading to the suppression of cell proliferation, migration, invasion, and induction of apoptosis in a concentration and time-dependent manner [112,113]. Here, TP53 is linked to renal cell carcinoma.