The intervention of 800 mg/kg/d green tea polysaccharides could up-regulate the expressions of CPT-1, down-regulate the expressions of PPARγ, SREBP-1c, FAS, and LXRα, thus significantly reducing the fat index and adipocyte area, and inhibiting mouse obesity [34,35]. This evidence concerns the gene SREBF1 and obesity due to melanocortin 4 receptor deficiency.