Still, this interaction between SR-A and IDE may be highly relevant in the field of oncology, as SR-A-dependent macrophage functions have been reported in endoplasmic reticulum stress-induced autophagy in macrophages [127], in tumor progression in ovarian and pancreatic cancer [128], as a marker of prognostic in prostate cancer [129], directly involved in tumour infiltration by the immune microenvironment and in the progression of colorectal cancer [130]. Here, MSR1 is linked to familial pancreatic carcinoma.