There are potential YB-1 binding sites in both the 5′- and 3′-untranslated regions (UTRs) of AURKA mRNA, and YB-1 promotes the expression of the AURKA protein by directly and specifically binding to AURKA mRNA, thereby promoting the proliferation and migration of NPC cells [92]. The gene discussed is YBX1; the disease is nasopharyngeal carcinoma.