CDK4 and glioblastoma: Similar results were obtained from other groups, who demonstrated that AGK2 induces growth inhibition in the sub-G0 (pre-G1) phase in glioblastoma cells [35] and in the sub-G0 and G1 phases in cervical cancer cells which were mediated by the decrease in cyclin D1, Cdk4 and Cdk6 expression [36].