PLOD1 and in situ carcinoma: The analysis of the proteome variation during time revealed that, depending on groups, about 20–30% of the proteins were already present at 2 h of culture and accumulated (CTRL = 15; LH = 15; CIS = 15; CIS + LH = 20), decreased (CTRL = 2; LH = 0; CIS = 0; CIS + LH = 2), disappeared (CTRL = 4; LH = 0; CIS = 0; CIS + LH = 1), remained stable (CTRL = 3; LH = 6; CIS = 5; CIS + LH = 9), or showed a variable pattern (CTRL = 7; LH = 7; CIS = 9; CIS + LH = 11), throughout the culture.