At this time, only 5 out of 55 potentially secreted proteins shared by all groups were present in statistically different amounts, Lyz2 and Saa3 in CIS vs. CTRL, Anti-dectin-1 15E2 heavy chain in CTRL vs. LH, Dag1 and Psap in CIS + LH vs. CTRL, and Psap in CIS + LH vs. LH (Figure 5 and Figure S2). This evidence concerns the gene CTRL and in situ carcinoma.