Likewise, statistical analyses performed on 18 potentially secreted proteins common to FCM of all groups or those shared by paired groups, revealed only a few differences related to the higher level of secreted Cst3 in CIS + LH in comparison to CTRL and CIS and of Dag1 and Anti-dectin-1 15E2 heavy chain in CIS + LH compared to LH (Figure S3). This evidence concerns the gene PLOD1 and in situ carcinoma.