AKR1A1 and in situ carcinoma: Exclusive of CIS + LH, Abracl, belonging to a novel family of low-molecular-weight proteins that increase actin dynamics, Akr1a1, a novel S-nitroso-glutathione reductase mediator of redox-based cellular signaling [40], Cdcc80, a member of the peroxiredoxin family of antioxidant enzymes [41], and Il4r, a component of the IL-4 receptor essential for tissue preservation and repair, were secreted [42].