Nagy et al., in their paper, have suggested that since Sin3A is associated with both NCoR and MAD1, they proved a convergence in the repression pathways associated with bHLH-Zip proteins and nuclear receptors [32] by demonstrating that HDAC inhibitors and retinoic acid synergistically stimulated hormone responsive genes and the differentiation of myeloid leukemia cells, which has been further confirmed by the present study. The gene discussed is SIN3A; the disease is myeloid leukemia.