TRPM7 and ischemia: During the 7 days post-ischemia period, we found that TRPM7 knockout in PV (PV-TRPM7−/−: 93.8%) and CaMKII (CaMKII-TRPM7−/−: 92.3%) neurons resulted in clear enhancement of animals’ survival rate in comparison with that of TRPM7flox/flox MCAO (control group: 63.6%, Figure 2C).