In pioneering studies using time-lapse cinemicrography extending for 7–10 days per experiment carried out between 1988 and 1995, Tamm and colleagues discovered that IL-6 had variable effects on the proliferation of breast cancer cells (enhance, inhibit, or no effect depending on cell clones investigated), but unexpectedly, caused a marked increase in breast cancer cell motility and dispersion of cells [3,4,43,44,45,46] (Figure 1 and Figure 2). Here, IL6 is linked to breast carcinoma.