CUL2 and cervical carcinoma: In addition, lncRNA LINC00997 was shown to activate the MAPK pathway-associated protein CUL2 by interacting with miR574-3p, demonstrating that the LINC00997/miR-574-3p/CUL2 axis contributes to proliferation, migration, invasion, and autophagy by activation of MAPK signaling in cervical cancer [44].