A further study demonstrated that ENC1 knockdown decreased the protein levels of p-p38, p-MEK1/2, and p-ERK1/2, inhibiting the activation of the ERK/MEK pathway and reducing cell proliferation, suggesting that the LOXL1-AS1/miR-423-5p/ENC1 axis accelerates cervical cancer development through the MEK/ERK pathway. The gene discussed is MAPK1; the disease is cervical carcinoma.