CNR1 and myocardial infarction: Multiple case reports have linked marijuana to thrombus formation, leading to acute MI [13], and the authors quote the publication by Deusch et al. [91] on human platelets in vitro in which CB1- and CB2-Rs are expressed and THC enhances expression of the platelet fibrinogen receptor (glycoprotein IIb-IIIa) and P-selectin; experiments with CB-R antagonists were not performed in that study.