Our results indicate that miRNAs target genes for upregulated and downregulated expression belong to the following classes: Pathways in cancer (STAT5A, MMP1, and CXCL12), microRNAs in cancer (HMOX1, GNAI2, and DVL2), proteoglycans in cancer (NRAS, DNMT3A, and CASP3), PI3K-Akt signaling pathway (ITGB4, ITGB3, and MTOR), and FoxO signaling pathway (STAT3, TGFBR1, and IL6). The gene discussed is ITGB4; the disease is cancer.