IL25 and asthma: Eosinophils and basophils have been described as the major source of IL-25 in patients with asthma, but a wide range of cells produce and secrete IL-25, including also epithelial/endothelial cells, activated Th2 cells, alveolar macrophages, bone marrow-derived mast cells, and fibroblasts [35,36,37,38,39,40,41].