For example, CPEB1 prevents breast cancer metastasis by reducing the poly(A) tail length and the expression of matrix metalloproteinase 9 [75], while CPEB4 promotes melanoma progression by modulating the expression of lineage-specific melanocyte-specific oncogenes, such as MITF (microphthalmia-associated transcription factor) and RAB7A, through cytoplasmic polyadenylation [76]. The gene discussed is MITF; the disease is melanoma.